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Breast Cancer, Beyond Convention
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Chapter One: A Diagnosis of Breast Cancer: Taking Your First Steps
Susan Love, M.D., M.B.A. SUSAN LOVE, M.D., M.B.A., is a researcher, author, activist, surgeon, and
founder of LLuminari,SM a multimedia women's-health content company,
and www.SusanLoveMD.com. As author of Dr. Susan Love's Breast Book
and Dr. Susan Love's Hormone Book, she has gained the trust of women
worldwide. She is currently the medical director of the Susan Love, M.D.,
Breast Cancer Foundation, a nonprofit organization dedicated to the eradication
of breast cancer, an adjunct professor of surgery at UCLA, a member of the
National Cancer Advisory Board, and a director of the National Breast Cancer
Coalition. Hearing the words "you have breast cancer" is shocking. The shock
can last for minutes to hours, and it is soon followed by questions: "How
can this be?" "What does this mean?" "Am I going to die?"
"What should I do?" Many people close at hand will try to answer your
questions and direct you on a path of treatment. But over the years I have learned
that treatment is not enough for most women. Most of us need to be healed as
well. Treatment is pretty easy to get and pretty standardized, but to feel healed,
you must put together a different plan that is unique to you. This often includes
what some people term alternative and conventional therapies. With a diagnosis of breast cancer you enter the world of the "sick."
Your modesty goes first. Your dignity is also left at the exam room door as
you walk around in a short hospital gown with your bare bottom exposed to the
world. You reveal intimate details about your body to perfect strangers, over
and over again -- but they never once ask you questions about who you are as
a person, who you love, and who loves you. You have ceased to be a unique contributing
person in the world and have become a "case." The treatments of breast
cancer, which I have called "slash, burn, and poison," are depersonalizing
and cold: "one size fits all." They may well improve the statistics
of survival, but they don't empower the woman who has to undergo them. In order
to reclaim the process you have to take control of your treatment and control
of how you are treated. You need to find ways that work for you to heal yourself
as well as treat this disease. You need to find your own way through the maze
of breast cancer, its practitioners, its standard therapies, and its complementary
treatments and form your own unique path to healing. All this takes time and energy, of course; neither is plentiful when you have
just been diagnosed with breast cancer. That is okay. You don't have to do everything
at once. Besides, a diagnosis of breast cancer is not an emergency. Most breast
cancers have been present for eight to ten years by the time you can see them
on a mammogram or feel them. They have either spread microscopically, or not
spread, by the time of diagnosis. Although you shouldn't spend the next six
months studying the problem, you do have time to catch your breath, get a second
opinion, and search out the options. It is important to start with an understanding of the current hypothesis of
breast cancer. Most breast cancer starts in the lining of the milk ducts. The
breast consists of approximately six to eight ductal systems. The ductal system
consists of lobules that make the milk and ducts that are the pipelines, carrying
milk to the nipple. We think that breast cancer is the result of a series of
steps. First there are an increased number of cells in the lining of the milk
ducts, almost like rust. This is called hyperplasia. The cells then become "funny
looking" and are then called atypical hyperplasia. After a time the cells
actually resemble breast cancer cells, but they are completely contained by
the ducts. This is called ductal carcinoma in situ, or DCIS (a similar progression
can be outlined in the lobules). Finally the cells invade outside of the ducts
into the surrounding fat and become invasive ductal cancer. This is what we commonly call breast cancer. Once breast cancer is invasive,
it has the ability to cause new blood vessels to grow in order to feed the tumor.
Soon after, cancer cells have the ability to invade the blood vessels and travel
throughout the body. The cells find a comfortable environment in other organs
and form new colonies of breast cancer cells. In fact, it is the breast cancer
cells elsewhere in the body that are life threatening. If they start to grow
they can interfere with vital functions in the liver, lungs, or brain and finally
lead to death. This whole process does not take place very rapidly. In fact, it is estimated
that the average breast cancer has been present for eight to ten years by the
time it can be felt as a lump or seen on a mammogram. It is also true that cancer
cells and colonies of cancer do not grow continuously in the body; more likely
they rest and grow over the years, depending in part on the environment in which
they find themselves. What triggers cancer cells to grow and become detectable
at one time rather than another? We really don't know, but we suspect that this
is where such factors as stress and the immune system may act. Women often speak
of getting cancer after a particularly stressful period of time, and wonder
whether the stress caused the cancer. This is unlikely, as it takes a long time
for the process to evolve. What is more likely is that the stress alters the
hormonal balance of the body and possibly depresses the immune system. This
imbalance may lead to stimulation of a quiescent colony of breast cancer cells,
causing them to multiply, divide, and possibly spread to other parts of the
body. This is what happens when a tumor reemerges after a period of dormancy.
What were those cells doing for ten years? They were asleep. What put them to
sleep? What woke them up? It is highly likely that the general status of health
and vitality in the person will have a major impact on the status of those cells.
Our belief that all cancer cells have to be killed may not be a good one after
all. This notion of killing comes in part from thinking about breast cancer
as a foreign invader that gets into the body and grows continuously until it
takes over. In fact, breast cancer starts in your own cells, which develop mutations,
allowing them to replicate without limit and invade outside their own territory.
These cancer cells are not in isolation. The cells around them, and the general
state of the body, influence their capacity to thrive. A criminal analogy might
work here. Some criminals have severe character defects that cannot be changed,
but many can be rehabilitated if they are put into another environment. Cancer
cells may also be able to be rehabilitated, reversed, or controlled if the environment
of cells, hormones, and the immune system around them is changed. This becomes
important in our approach to treating breast cancer. When I first started in
this field twenty-five years ago, we did not have chemotherapy. Instead, if
a premenopausal woman was diagnosed with breast cancer, we would take out her
ovaries. Interesting new studies have monitored these women, and it turns out
that taking out a woman's ovaries is as effective as chemotherapy in premenopausal
women with estrogen receptor-positive cancers. Why would putting a woman into
menopause treat her breast cancer? It does not kill cells the way that chemotherapy
does. What it does do is change the environment for the cells by changing the
hormonal milieu. The cells are probably "put to sleep" and stay asleep
unless something comes to wake them up. All of this becomes important in the way we approach breast cancer therapy.
Our current therapies of chemotherapy, surgery, and radiation therapy, albeit
the best we have, are crude ways of dealing with the disease. They have been
shown to make some difference in survival from breast cancer, but they are focused
on killing cancer cells rather than changing their environment. Hormonal therapies,
immune approaches, mind-body techniques, nutritional treatment, and other alternative
treatments focus on strengthening the body and altering the immune system to
make important changes in the internal environment. With this understanding, it becomes obvious that we need to address newly diagnosed
breast cancer on three different fronts. The first is to do something that will
prevent breast cancer from recurring in the breast. This is called local therapy
and usually involves surgery to remove the cancer, in combination with radiation
therapy to clean up any microscopic cells that have been left behind. The surgery
is usually a lumpectomy or wide excision around the original tumor, but it can
be a mastectomy if the mass is so large that it cannot be removed any other
way. It is very interesting that chemotherapy will not always take care of this
bulk of cancer cells in the breast. It seems that systemic therapy, regardless
of whether it is chemotherapy, hormone modulation, or alternative medicine,
works better on microscopic cells than on chunks of cancer. In all of these
situations, surgery still appears to be the best way to debulk, or remove, the
chunks of cancer. Local therapy can be curative if -- and it is a big if --
the body has either taken care of all the cells that may have gotten out or
reversed them. The next phase is systemic therapy. We presume that cells from most cancers
have escaped through the bloodstream and "gotten out." These cells
will seed other organs, and they can grow and affect these distant organs later
on. Systemic therapies are those which are given by mouth or vein, get into
the bloodstream, and therefore have a chance of affecting these cells. The most
common systemic therapy is chemotherapy, with drugs that interfere with cell
division and, as such, poison cancer cells as well as some normal cells. Hormonal
therapy with agents such as tamoxifen, by contrast, changes the environment
of the cell and probably acts more to control or reverse cancers. The third aspect of treatment is to strengthen the body and immune system so
that they can better reverse or control the cancer cells. This is where nutrition,
exercise, meditation, visualization, support groups, and other alternative techniques
come in. They are as important as the drugs. We all know women who have small
cancers, with good prognoses, who get all the standard traditional therapies,
yet rapidly succumb to the disease. By contrast, some women whom we expect to
do poorly live -- to everyone's surprise. There is no question in my mind that
these results are in part attributable to holistic approaches to disease. Data
from new studies are showing that women who are overweight have a higher rate
of recurrence than women who are not overweight. Exercise has been demonstrated
to prevent breast cancer and may well help prevent recurrence. David Spiegel
has demonstrated that women with metastatic disease who participated in support
groups lived 18 months longer than women who did not.1 Can alternative therapies
cure cancer by themselves? I don't know, but I would not personally risk it.
On the other hand, can standard therapies cure cancer by themselves? I don't
know, but I certainly would not risk doing one without the other. And what about metastatic disease? Metastasis occurs when the cancer has been
treated and then returns in other organs of the body: lungs, liver, bones, or
brain. Again, the standard therapies are limited. We try different hormonal
and chemotherapy drugs as well as radiation in an attempt to get the cancer
back into remission, but we are not generally able to cure breast cancer at
this point. Can we control it? We certainly try -- and again, it is here that
complementary therapies are important. If we believe that a change in the environment
of the body is what causes the cancer to wake up, then we certainly need a change
in the environment of the body to put it back to sleep. In addition to facing the shocking news of breast cancer and choosing specific
treatment options, you still have to deal with the many debilitating side effects.
In some ways, this is the most important time for women, since this is frequently
when healing takes place. Tissues that have been damaged by chemotherapy, surgery,
and radiation can be healed by nutrition and exercise. Acupuncture has been
used successfully to treat postsurgical pain, chemotherapy-related nausea and
vomiting, and the fatigue induced by radiation. Traditional Chinese medicine,
herbs, and other therapies have been used to help women with breast cancer deal
with the symptoms of premature menopause and the side effects of tamoxifen.
The body clearly needs to be rebalanced after the assault from cancer therapy.
Nutritional, physical, and spiritual rebalancing will make the difference. How can a woman put together the best approach to treat her disease and heal
herself? When she is newly diagnosed with breast cancer or discovers a recurrence,
she needs to first put together a team of experts that includes a breast cancer
specialist she can trust and work with, who will help guide her. This could
be a surgeon, an oncologist, a radiation therapist, or even a primary care physician.
It is important that each person feels comfortable with her care providers and
acts as a partner in her team. This may mean shopping around. Many medical doctors are scared of alternative therapies, probably because
they don't know much about them. Many of their criticisms do not hold water
when examined closely. Although they often cite an absence of scientific studies
of alternative therapies, they will often suggest drugs that have yet to be
proved effective by the "gold standard" of randomized controlled clinical
trials. The recent experience when thirty thousand women underwent high-dose
chemotherapy with stem cell rescue before studies demonstrated that it was not
better than standard chemotherapy is a perfect example of how modern medicine
is not always based on science. Some doctors complain that alternative therapy
is not standardized; yet, these same physicians will argue that modern medicine
cannot be dictated by insurance companies because it is not standardized. Finally,
they suggest that alternative therapy is too personality driven, but at the
same time, we often search for the "best" surgeon or oncologist with
the understanding that the person delivering the care is as important as the
care. In reality, these physicians are uncomfortable because they have not been
trained in that tradition and do not feel knowledgeable about its use. By explaining
to your physicians what you are doing, you can often educate them. Ask your
alternative practitioners for information that you can share with your medical
team. Your experience may well pave the way for the next woman with breast cancer
who wants to explore a broader range of healing. Not only is it important to find the right team of medical doctors, but you
must find the right team of alternative practitioners as well. There is no advantage
to walking into a health food store and picking herbs and supplements off the
shelf and combining them willy-nilly. Different herbs have different effects
and may or may not lend themselves to combinations. It is important that you
see a trained herbalist, naturopath, or traditional Chinese medicine doctor
who can guide you in this approach. Ask for their credentials and training;
talk to people whom they have treated. Nutritionists and personal trainers will
also be important in helping you revise your lifestyle in a more healthy manner.
Look for a counselor experienced with breast cancer survivors and/or a support
group to help your emotional healing. Find the best approach for your spiritual
healing, whether in traditional religion, yoga, meditation, or your own personal
journey. All of this is important. After a diagnosis of breast cancer, your
life will never again be the same. But it can be better as you put together
your approach to therapy and healing from this disease. This is an individual journey -- one that is unpredictable. We all desire magic:
"If I just eat this, take this herb, and do this exercise, the cancer won't
come back again." There is no magic. One of my patients had a very small
tumor, with prognostic factors that were all good. She begged us to give her
chemotherapy even though we had no statistical evidence that the medicine would
benefit her. She just "felt" that she had a bad tumor and needed it.
We finally gave in and treated her with our most aggressive regimen. She changed
her life, but within two years she was dead of metastatic breast cancer. On
the other hand, one of my very first patients was a young woman with a very
aggressive type of breast cancer. Not only was the tumor large, but also she
had twenty positive lymph nodes. She underwent standard chemotherapy and radiation
before revamping her life. She left her husband, moved to Hawaii, and started
a nutrition and spiritual program that completely changed her life. She is still
alive and well twenty years later. I tell these stories not because I think that we can control all cancers with
alternative approaches, but rather because I think they demonstrate how little
we understand about this disease. We do what we can with standard therapy, but
we base our therapies on statistics and large randomized studies, which tell
us very little about any one woman, her body, and her cancer. There is no right
or wrong way to treat breast cancer. There is only your way. Whatever happens
to you is 100% yours, regardless of the purported statistics. Putting together
your own personal prescription for treatment and healing will ultimately be
the best approach for you. This magnificent collection of chapters will help
you with that journey.
Excerpted from Breast Cancer, Beyond Convention: The
World's Foremost Authorities on Complementary and Alternative
Medicine Offer Advice on Healing by Mary Tagliaferri, Isaac Cohen, Debu Tripathy.
Copyright © 2002 by Mary Tagliaferri, Isaac Cohen, Debu Tripathy. All rights reserved.
No part of this excerpt may be reproduced or reprinted without
permission in writing from the publisher.